OpenFocus aligns and combines multi-focus image sequences to produce images with focus across the frame.
Alternatives to Focus Stacking Online
Focus Stacking Online merges photos of the same scene taken at different focus distances, blending their sharp regions into one image. Its browser workflow is direct: add pictures, select an alignment method and reference picture, stack, then download. It is free to use online, needs no software installation, and works on laptops and smartphones. The maker describes it as particularly useful for macro photography, where shallow depth of field can leave parts of a subject…
CKAN is a free, open-source metadata repository and toolset for finding, installing, and managing Kerbal Space Program mods.
ImageFocus Alpha is free software for capturing and analyzing microscope images, designed for compatible Euromex camera models.
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focus-stack
focus-stack is a free tool that combines photos taken at different focus settings into an image with greater depth of field.
Free planLinuxmacOSWindows6.5Free plan - 5
CombineZP
CombineZP is Windows software for focus stacking: it combines in-focus areas from multiple photographs to create an image with greater depth of field.
Free planWindows6.4Free plan - 6
Helicon Focus
Helicon Focus combines photographs taken at different focus distances into one image with extended depth of field.
macOSWindows6.4 - 7
PlaneFuse
PlaneFuse is free focus-stacking software for macro, product, and landscape photography.
Free planWebAPILinuxmacOS6.4Free plan - 8

Zerene Stacker
Zerene Stacker is focus stacking software for photographers working with macro subjects, including challenging details such as hairs and bristles.
LinuxmacOSWindows6.4$39 one-time - 9
Open Galileo
Open Galileo is free, open-source desktop software for focus stacking and signal integration.
Free planWindows6.3Free plan - 10
ChimpStackr
ChimpStackr is a free, open-source application for focus stacking, available with a graphical interface and a headless command-line tool.
Free planLinuxmacOSWindows6.2Free plan - 11

Macro Studio
Macro Studio is desktop focus-stacking software for macro photography, combining focus-bracket images with non-destructive editing tools.
LinuxmacOSWindows6.2$59 one-time - 12

Rekall Fusion
Rekall Fusion is Windows software that aligns focus-stack frames and combines them into one image sharp from front to back.
Windows6.2From $20 a year - 13

FOCUS projects 4 professional
FOCUS projects 4 professional is a standalone photography application from FRANZIS GmbH for creating macro images with extended depth of field.
macOSWindows6.1€20 one-time - 14
ForgePix
ForgePix is free beta software for focus stacking and computational photography, designed for macro, astrophotography, and long-exposure image series.
Free planLinuxmacOSWindows6.1Free plan - 15
Vitamin-R
Vitamin-R is a paid macOS focus and time-boxing app that turns a task into a defined work session.
macOS6.1$29.95 one-time - 16

Aduku Stacker
Aduku Stacker combines photographs taken at different focus distances into a sharp image, for macro, product, landscape, and microscopy photography.
Free planmacOSWindows5.9Free plan - 17
PICOLAY
PICOLAY is a free Windows program that builds improved images from picture series.
Free planWindows5.9Free plan - 18

Shine Stacker
Shine Stacker combines images captured at different focus distances to create an image with greater depth of field.
Free planAPILinuxmacOSWindows5.9Free plan - 19
PhotoAcute Studio
PhotoAcute Studio is image-processing software from Almalence for combining sets of photographs, particularly shots taken in continuous mode.
LinuxmacOSWindows5.8 - 20
TuFuse
TuFuse is a Windows command-line program that combines the best-exposed and/or best-focused regions of multiple images into one composite.
Free planWindows5.8Free plan - 21
FocusFusion
FocusFusion combines photographs taken at different focus distances into a single image with greater depth of field.
Free planWindows5.7Free plan - 22
Enfuse
Enfuse is a free command-line program that combines different exposures of the same scene into an image without first creating an HDR image.
LinuxmacOSWindows5.6 - 23
Ashampoo FOCUS #6
Windows4.5