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OpenFocus

OpenFocus aligns and combines multi-focus image sequences to produce images with focus across the frame.

Place
#2 of 24
Score
7.1
OpenFocus's website

What OpenFocus is

OpenFocus aligns and combines multi-focus image sequences to produce images with focus across the frame. It runs on Linux, macOS, and Windows, with a graphical interface for Windows and macOS and a command-line interface on all three platforms. Alignment options include ECC and Homography; fusion choices include Guided Filter, DCT, DTCWT, GFG-FGF, and the StackMFF V4 AI model. A draggable wipe view compares source frames with results, and the software can generate per-pixel maps of focus position. OpenFocus processes folders in batches and can run headlessly for scripts and CI. Listed inputs include JPG, PNG, BMP, TIFF, MP4, and numbered image folders; the manual also describes decoding additional video formats. Exports include those image formats, image-sequence folders, and GIF animations. Research-oriented tools include scale bars calibrated from image metadata and multi-page TIFF stacks that preserve 16-bit depth. The interface supports English, Chinese, Japanese, and Spanish, with system-language detection. The software is free under the MIT License, though included algorithms may have separate terms.

Good

  • Offers five listed fusion methods
  • Supports folder batches and headless command-line use
  • Can create per-pixel focus-position maps
  • Preserves 16-bit depth in multi-page TIFF stacks

Watch out

  • Windows and macOS builds are unsigned
  • Included algorithms may have separate license terms
  • Graphical interface is listed for Windows and macOS

Who it suits

OpenFocus suits researchers, engineers, and image-processing professionals working with multi-focus image sequences. Its batch and command-line options may also suit users who need folder processing or scripted workflows.

Verdict

OpenFocus brings alignment, fusion, inspection, and batch tools together for multi-focus images. Check the unsigned-build warnings and any separate algorithm license terms before using it.

Plans and prices

From OpenFocus's own pricing page, checked 15 Oct 2026.

All about pricing
PlanPriceWhat it gives you
Free and open sourceFreeWindows/macOS GUI · Linux CLI · MIT source license

The facts

Each one read from OpenFocus's own pages, with the date it was checked.

What it does

3D export
Version 1.54–1.55 added textured OBJ export combining a depth map and fused image.checked 15 Oct 2026
Algorithm limitation
OpenFocus A produces a deliberately soft look and is not intended for the supplied benchmark.checked 15 Oct 2026
Batch and CLI
It supports batch processing across folders and a headless command-line interface for scripting and CI.checked 7 Oct 2026
Batch processing
The application can process multiple folders with progress reporting, cancellation and organized outputs.checked 15 Oct 2026
Command line
A pip-installable headless CLI runs on Windows, macOS and Linux and returns exit codes 0, 1 or 2 for success, processing errors or usage errors.checked 15 Oct 2026
Compare and inspect
A wipe compare view uses a draggable divider to compare source frames and results, and the software can generate per-pixel focus-position depth maps.checked 7 Oct 2026
Depth maps
Index-deciding fusion methods can produce per-pixel focus-position maps with pseudo-color display and 16-bit export.checked 15 Oct 2026
Documentation
The project links an English manual, Chinese manual, changelog, large-stack performance notes and build commands.checked 15 Oct 2026
Exports
The manual lists JPG, PNG, BMP, TIFF, image-sequence folders, and GIF animations as output options.checked 7 Oct 2026
Extensibility
Source builds use Python 3.10 with requirements.txt, and PyInstaller packaging instructions are provided.checked 15 Oct 2026
Feature limitation
The comparison table lists camera or rail control as unavailable in OpenFocus.checked 15 Oct 2026
Fusion methods
Fusion options include Guided Filter, DCT, DTCWT, GFG-FGF, StackMFF V4 and OpenFocus A/B/C.checked 15 Oct 2026
GPU limitation
GPU acceleration is optional and is provided for the StackMFF V4 neural model.checked 15 Oct 2026
Image alignment
It offers ECC and Homography methods to align image sequences.checked 7 Oct 2026
Input formats
The manual lists JPG, PNG, BMP, TIFF, MP4, and numbered image folders as supported inputs; it also describes decoding several additional video formats.checked 7 Oct 2026
Intended users
The manual describes OpenFocus as a desktop application for researchers, engineers, and image-processing professionals.checked 7 Oct 2026
Interface
The desktop application is built with PyQt6 and supports CPU processing by default.checked 15 Oct 2026
Languages
The interface supports English, Chinese, Japanese, and Spanish, with automatic system-language detection.checked 7 Oct 2026
License
The repository is released under the MIT License.checked 15 Oct 2026
License caveat
Included research algorithms may carry original license terms in addition to the OpenFocus MIT license.checked 15 Oct 2026
Microscopy features
The software supports TIFF µm-per-pixel calibration, dust-map flat-field correction and publication scale bars.checked 15 Oct 2026
News: 2026-10-15
The project announced OBJ export, camera RAW support and depth smoothing for OpenFocus B on October 15, 2026.checked 15 Oct 2026
News: 2026-10-15 retouch
A same-day release added the retouch brush, live progress, per-method kernel memory and improved DTCWT and GFG-FGF behavior.checked 15 Oct 2026
Output formats
Exports include JPG, PNG, WebP, BMP and TIFF, with 16-bit data preserved through the pipeline.checked 15 Oct 2026

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