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Mirth Connect

Mirth Connect is a healthcare integration engine for routing, filtering, and transforming messages between health information systems.

Place
#32 of 113
Score
7.5
Mirth Connect's website

What Mirth Connect is

Mirth Connect is a healthcare integration engine for routing, filtering, and transforming messages between health information systems. It supports bidirectional exchange and offers tools for protocol conversion, advanced mapping, and channel mapping that users can create, test, and deploy. Listed formats include HL7 v2.x and v3.x, CSV and other delimited text, DICOM, EDI/X12, XML, JSON, NCPDP, and raw data. Transfer methods include MLLP, TCP/IP, HTTP, files, databases, SFTP, FTP, SMB, WebDAV, email, DICOM, JMS, SOAP, and custom Java or JavaScript. The product page describes EHR and practice-management read/write across 800+ integration routes, plus a FHIR-enabled Patient Access API and SMART on FHIR support. Customers can self-host the engine or host it in NextGen’s co-located US data centers or AWS environment. The customer operates the licensed engine and builds and supports interfaces in-house. A complimentary research license is limited to active studies affiliated with a nonprofit institution. Other tiers use annual per-server licensing, with pricing available on request and included support varying by tier.

Good

  • Routes, filters, and transforms healthcare messages bidirectionally.
  • Supports HL7, DICOM, EDI/X12, XML, JSON, and other formats.
  • Offers self-hosting and hosted deployment options.
  • Includes a complimentary license for eligible nonprofit research studies.
  • License tiers include unlimited support cases per year.

Watch out

  • Pricing for paid tiers is available on request.
  • Customers operate the engine and support interfaces in-house.
  • Extensions are only available with a Mirth Connect license.

Who it suits

Mirth Connect suits healthcare organizations that need to route and transform messages between health information systems. The customer-responsibility model is relevant for teams prepared to operate the engine and support interfaces in-house.

Verdict

Mirth Connect covers a broad set of healthcare message formats, transfer methods, and deployment choices. Buyers should account for the customer’s responsibility to run the engine and build and support interfaces, as well as request pricing for paid tiers.

Plans and prices

From Mirth Connect's own pricing page, checked 14 Oct 2026.

All about pricing
PlanPriceWhat it gives you
Mirth Connect for ResearchFreeComplimentary license for approved active studies affiliated with a nonprofit institution
EnterprisePriced on requestUnlimited support cases · 50 channel-analytics channels · SSL Manager, Channel History, Message Generator · Success Community access
GoldPriced on requestUnlimited support cases · 100 channel-analytics channels · 24x7 phone support · broader extension bundle
PlatinumPriced on requestUnlimited support cases · 200 channel-analytics channels · 24x7 phone support · advanced clustering and alerting

The facts

Each one read from Mirth Connect's own pages, with the date it was checked.

What it does

Administration
The architecture includes a server, Java Administrator client, Server Manager and command-line interface for channel deployment and administration.checked 14 Oct 2026
API and SDK depth
The extension documentation identifies a mirth-core-client library with a Client class for server API requests and servlet interfaces for API hooks.checked 14 Oct 2026
API capability
The product page describes an enterprise API for read/write EHR and practice-management access across more than 800 integration routes.checked 14 Oct 2026
Connectors
The product supports protocol and transport integrations such as HTTPS, TCP, SFTP, HL7, DICOM, web services and file-based exchange.checked 14 Oct 2026
Current licence
Starting with version 4.6 released March 19, 2025, new releases use a closed-source proprietary commercial licence and their source code is not published.checked 14 Oct 2026
Customer responsibility
The licensed Mirth Connect engine is maintained and operated by the customer, who builds and supports interfaces in-house.checked 7 Oct 2026
Databases
Supported message-store databases include Apache Derby, PostgreSQL, MySQL, Oracle and Microsoft SQL Server.checked 14 Oct 2026
Data retrieval
Mirth Connect can automate patient-data queries and retrieval from external EHR systems.checked 14 Oct 2026
Data transformation
Yeschecked 22 Sep 2026
Deployment
The server is a standalone application that runs in its own JVM and does not require an application server.checked 14 Oct 2026
Documentation
NextGen provides a user guide covering system requirements, installation, administration, connectors, upgrades and licensing FAQs.checked 14 Oct 2026
Extensibility
Custom extensions can use client, server-plugin, model, UI and utility core libraries, and can implement custom connector plugins.checked 14 Oct 2026
Extensions
Mirth Connect extensions are only available as part of a Mirth Connect license and are not sold individually.checked 7 Oct 2026
FHIR
The product includes a built-in Patient Access API that is FHIR enabled and supports SMART on FHIR embedded applications.checked 14 Oct 2026
FHIR and APIs
The product page describes an enterprise API with EHR and practice management read/write across 800+ integration routes, a FHIR-enabled Patient Access API, and SMART on FHIR support.checked 7 Oct 2026
Formats
The product documentation lists support for HL7 v2.x and v3.x, CSV and other delimited text, DICOM, EDI/X12, XML, JSON, NCPDP, and raw data.checked 7 Oct 2026
Healthcare reach
NextGen says Mirth Connect powers one third of public health information exchanges and is used in more than 40 countries.checked 14 Oct 2026
HIPAA
Mirth Fully Managed is described as fully encrypted with built-in HIPAA compliance and multi-availability-zone disaster recovery.checked 14 Oct 2026
Historical licence
The last published open-source line, version 4.5.2, was released under Mozilla Public License 2.0.checked 14 Oct 2026

The company

Company founded
Crunchbase states that NextGen Healthcare was founded in 1974.checked 14 Oct 2026
Company headquarters
Crunchbase places NextGen Healthcare in Irvine, California, United States.checked 14 Oct 2026
Company legal name
Crunchbase lists the legal name as NextGen Healthcare Inc.checked 14 Oct 2026
Company size
LinkedIn lists NextGen Healthcare as a privately held software-development company with 1,001–5,000 employees.checked 14 Oct 2026
Founded
1974checked 28 Sep 2026
The full review of Mirth Connect

Overview

Mirth Connect is an integration engine for moving clinical data between separate health information systems. It is best suited to healthcare organizations with integration staff who can build and maintain interfaces; its breadth is useful, but customers operate the engine and support their own interfaces.

It brings together a wide range of healthcare formats, transports, and deployment options. The main qualification is commercial and operational: licenses for version 4.6 and later are proprietary and paid, and the customer remains responsible for running the software.

Key features

Mirth Connect routes messages in both directions, with filtering, transformation, real-time synchronization, and workflow orchestration. Supported formats include HL7 v2.x and v3.x, CSV and other delimited text, DICOM, EDI/X12, XML, JSON, NCPDP, and raw data. Transfer methods include MLLP, TCP/IP, HTTP, files, databases, SFTP, FTP, SMB, WebDAV, email, DICOM, JMS, SOAP, and custom Java or JavaScript. That range can help integration teams connect systems that differ in both data format and transport, though the organization must design and support the resulting interfaces.

Transformation tools cover protocol conversion, advanced mapping, and channel mapping, with channels users can create, test, and deploy. The product page also describes an enterprise API with read/write access across more than 800 EHR and practice management integration routes, a FHIR-enabled Patient Access API, and SMART on FHIR support. NextGen says the engine is used in over 40 countries and handles the exchange, import, and export of 340 million clinical documents annually; these figures point to substantial use, not a substitute for assessing a particular deployment's requirements.

Organizations can self-host or use NextGen's co-located US data centers or AWS cloud environment. That choice gives teams options for where the engine runs, but does not transfer responsibility for maintaining and operating a licensed engine from the customer. Extensions are available only with a Mirth Connect license, not as individual purchases.

Pricing

Mirth Connect's listed plans use flat-fee annual licensing per server, with custom pricing for the paid tiers. The complimentary Mirth Connect for Research plan costs nothing and is limited to active research studies affiliated with a non-profit institution; eligibility is verified. It is a narrow option for qualifying studies rather than a general free tier.

Enterprise includes unlimited support cases per year, 50 channel analytics, SSL Manager, and Mirth Command Center access. Gold adds 24x7 phone support and 100 channel analytics, while Platinum includes 24x7 phone support and 200 channel analytics. Both Gold and Platinum include extensions; the Enterprise plan's listed inclusions do not. All three paid plans have unlimited support cases, but the higher tiers add phone coverage and progressively more channel analytics. Contact sales for Gold and Platinum pricing; Enterprise also has custom pricing. Starting with version 4.6, a purchased license is required to upgrade, and the license is proprietary.

Platforms

The installer supports Windows, Linux, and macOS. The product's platform coverage also includes API, web, and self-hosted environments. Self-hosting suits organizations that want to run the engine themselves; NextGen-hosted options are co-located US data centers and AWS.

Who it's for

Mirth Connect fits healthcare organizations that need to exchange data across disparate systems and have the staff to build, operate, and support interfaces in-house. Its format and protocol breadth, mapping tools, and deployment choices are relevant to complex integration work. It is a weaker fit for buyers seeking a turnkey service that takes responsibility for interface operations, or for teams that cannot support a licensed engine.

Pros and cons

  • Broad format and transport coverage: Support for healthcare standards, common data formats, and many transfer methods helps bridge systems with different integration requirements.
  • Flexible mapping and deployment: Users can create, test, and deploy channel mappings, while organizations can self-host or use NextGen's co-located US data centers or AWS.
  • Customer-owned operations: The customer maintains and operates the engine and builds and supports interfaces, making internal integration capacity a prerequisite.
  • Paid proprietary upgrades: Version 4.6 and later require a purchased license, and extensions are only available with a license, limiting the appeal of a free starting point for general use.

Alternatives

For billing-focused workflows rather than an integration engine, medical billing software and revenue cycle management software are relevant categories. Organizations comparing hosted integration services can also browse integration platform as a service software.

  • Office Ally Practice Mate is a freemium, web- and Windows-based option with a free Practice Mate plan covering appointment scheduling, patient billing, configurable superbills, a patient ledger, and reports; transactional fees may apply.
  • PracticeSuite Medical Billing is a paid alternative with custom pricing, modular features, and unlimited administrative users, suited to buyers seeking medical billing software rather than a general integration engine.
  • Nextech is a paid option for buyers considering software available on iOS, macOS, web, and Windows.
  • Oracle Health Revenue Cycle is a paid alternative with custom pricing for organizations looking specifically at revenue cycle products.
  • Tebra has a Practice Essentials low-volume plan starting at $199 a month per provider for 100 or fewer claims per month, for readers comparing a priced billing option.
  • EZClaim offers a First (Single) User annual plan priced at $189 a month; additional users and clearinghouse fees may add cost, making it a billing option to compare when that workflow is the priority.
  • TotalMD is a paid alternative with a free trial for buyers considering medical billing software.
  • AKASA Platform is a paid API- and web-based alternative.

Verdict

Choose Mirth Connect if your healthcare organization needs broad message routing and transformation and has the staff to build, operate, and support interfaces. Its strongest case is the combination of format and protocol coverage, mapping capabilities, and deployment options. Look elsewhere if you need a provider to take on interface operations, or if proprietary licensing and paid upgrades do not suit your requirements.

Getting started

  1. Review the Mirth Connect product page and contact sales for annual license pricing.
  2. Choose self-hosting or hosting in NextGen’s co-located US data centers or AWS environment.
  3. Install on Windows, Linux, or Mac OS X or macOS.
  4. Build, test, and deploy interfaces using the transformation and channel-mapping tools.
  5. Eligible active nonprofit research studies can seek the complimentary research license.

Limits worth knowing

The complimentary plan is limited to active studies affiliated with a nonprofit institution. Other listed tiers use annual per-server licensing, with pricing available from sales; extensions are only available with a Mirth Connect license.

Questions

Is Mirth Connect free?

A complimentary license is available for active research studies affiliated with a nonprofit institution. Other license tiers are paid.

How is Mirth Connect priced?

The listed paid tiers use flat-fee annual licensing per server, with pricing available from sales.

Can Mirth Connect be self-hosted?

Yes. Customers can self-host it or use NextGen’s co-located US data centers or AWS cloud environment.

What formats and protocols does it support?

Listed formats include HL7, DICOM, EDI/X12, XML, JSON, CSV, NCPDP, and raw data. Transfer options include MLLP, TCP/IP, HTTP, files, databases, SFTP, FTP, SMB, WebDAV, email, JMS, SOAP, and custom Java or JavaScript.

Does Mirth Connect support FHIR?

The product page describes a FHIR-enabled Patient Access API and SMART on FHIR support.

Is Mirth Connect open source?

Starting with version 4.6, NextGen says Mirth Connect uses a closed-source proprietary license; a license is required to upgrade to version 4.6 or later.

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