LibreSprite
8.0#1 in pixel art softwareFree planFree planAndroidWebAPILinux
VisitLibreSprite suits people making 2D sprites and animations who want layer, frame, palette and pixel-drawing tools. It runs on Windows, macOS, Linux and Android.
PixelWall suits people making pixel art, animations, or tilemaps who want local browser or desktop tools. It also offers automation options including a CLI, command API, JSON batches, and bounded Lua scripts.