GENOME

GENOME is a guitar-and-bass amp, effects and cabinet processor for players who want to shape sounds in a standalone app or a DAW. It is best suited to musicians who value capture compatibility and flexible routing; its compact free tier and separate iOS license narrow the appeal for others.

Overview

GENOME combines amp modeling, effects and virtual cabinets, with its CODEX engine loading Neural Amp Modeler, AIDA-X and Proteus captures. The product includes more than 40 premium AI amp captures, giving players a broad starting palette alongside those compatible formats.

Series or parallel signal paths can hold up to 12 components per lane, with dual-lane expansion for more involved routing. That flexibility suits players who want to build and control a signal chain in software, though using GENOME requires a Two notes account.

Key features

Amps, cabinets and effects

The paid plan includes 24 amps, 49 pedals, 16 DynIR cabinets and 16 Studio FX; the product also counts 65 effects overall and includes an IR loader. FairTone and Artist Series premium components are excluded, so the core collection is not the whole premium catalog.

Control and hardware

Parameter automation, MIDI mapping and MIDI Learn allow settings to be controlled from a DAW or external MIDI hardware. Compatibility with Two notes Captor, Captor X, OPUS and ReVolt hardware is a useful fit for players already using that ecosystem.

Standalone and DAW use

GENOME runs standalone or as a VST3, AU or AAX plugin. Two notes lists Pro Tools, Logic Pro X, Ableton Live, Cubase, Studio One and Reaper as tested DAWs, giving users of those hosts a clear path to plugin use.

Pricing

GENOME Intro is free and includes 4 TSM-Ai amplifiers, 14 pedals, 5 DynIR cabinets and 4 Studio FX. It is a practical way to start without paying, but its smaller selection makes it less suitable for players who need the breadth of the paid collection.

GENOME costs $89.99, paid once. It adds the 24 amps, 49 pedals, 16 DynIR cabinets and 16 Studio FX, while still excluding FairTone and Artist Series premium components. This one-time purchase suits players who want a larger core library without a recurring plan; the free tier is the better fit for a limited starting setup.

Both GENOME and its components can be tried with a 14-day free trial license. A desktop license does not include GENOME iOS, which requires a separate iOS Access Pass.

Platforms

GENOME is available for macOS 10.15 or newer, Windows 64-bit and iPad running iOS 12 or newer. Desktop users can choose standalone or plugin operation; iPad support is a separate purchase rather than an extension of a desktop license.

Who it's for

GENOME makes the most sense for guitarists and bassists who want amp, effects and cabinet processing in one app, especially those using NAM, AIDA-X or Proteus captures, MIDI control, or compatible Two notes hardware. Players who need a broad set of premium components beyond the included collection, or want iPad access bundled with desktop, should look elsewhere.

Pros and cons

Pros

• Loads NAM, AIDA-X and Proteus captures in one workflow, which avoids restricting users to one of those capture formats.
• Series and parallel routing, dual lanes and up to 12 components per lane leave room for elaborate software signal chains.
• Standalone operation and VST3, AU and AAX formats support both independent use and DAW sessions.
• The free Intro tier and 14-day trial provide ways to start before committing to the paid license.

Cons

• Intro includes only 4 amps, 14 pedals, 5 cabinets and 4 Studio FX, limiting the free collection.
• The $89.99, paid once license excludes FairTone and Artist Series premium components.
• iPad use requires a separate Access Pass, so the desktop license does not cover every supported platform.
• A Two notes account is required to use the software.

Alternatives

Guitar Amp Software is the category directory for comparing more options. Choose Amp Locker if Linux support matters or you prefer a free download with extra modules purchased individually and owned outright. IK Multimedia ReSing is another freemium choice, but its listed focus is voices and instruments rather than amp processing.

Neural Amp Modeler is worth considering for a free, open-source option with Linux and web support, particularly if you want to contribute to the project. Amped offers a free Roots amp and a full-license option for players comparing a more focused amp-software route. Amplifikation 360 is another freemium macOS and Windows option.

Helix Stadium Native has a no-time-limit Intro tier with 5 Agoura amps, 5 cabs and 15 studio effects, making it a concrete free-tier alternative. AIDA-X is a free choice with Linux, web and self-hosted platform support. Choose TH-U if you want to consider a paid product with a free trial and iOS support.

Verdict

Choose GENOME if you want a single guitar-and-bass processor with broad capture compatibility, flexible routing and both standalone and plugin workflows. Its free tier and trial make it accessible to explore, while the paid collection is a sensible fit for players who can work within its included components. Look elsewhere if you need the excluded premium content or expect desktop purchase to include iPad access.