Advarra OnCore
Advarra OnCore is a clinical trial management system for organizing research operations throughout a trial’s lifecycle.
What Advarra OnCore is
Advarra OnCore is a clinical trial management system for organizing research operations throughout a trial’s lifecycle. It supports protocol and participant workflows alongside budgeting, invoicing, receivables, and billing compliance. The system connects with Epic and Cerner to exchange subject, protocol, demographic, and billing information with EMR systems. Other listed integrations include eIRB through the OnCore API, EMR billing grids, general ledger, OnCore Analytics, and Advarra Payments. Optional capabilities cover biospecimens, protocol review, registries, and Advarra EDC technology for investigator-initiated trials. OnCore Analytics presents information about accrual, study activation, staff effort, and other operations. Advarra also describes support for cancer-center reporting, including NCI reporting and PRMC workflows. The cloud service is hosted on AWS, with system management and support from cloud technology experts. Advarra says its cloud platform meets SOC 2, HIPAA, 21 CFR Part 11, and NIST 800-53 standards. Pricing is on request; the annual subscription covers license, maintenance, support, and upgrades, while additional modules may be licensed separately.
Good
- Supports protocol, participant, and finance workflows.
- Connects with Epic and Cerner.
- Analytics covers accrual, activation, and staff effort.
- Cloud platform is described as meeting listed compliance standards.
Watch out
- No free plan is listed.
- Pricing requires contacting sales.
- Additional modules may be licensed separately.
Who it suits
OnCore is intended for academic medical centers, cancer centers, and some health systems managing 50 to 500+ active trials. Its connected research, finance, and reporting workflows suit organizations coordinating clinical trial operations across departments.
Verdict
OnCore brings trial workflows, financial processes, integrations, and operational analytics into a clinical research management system. Pricing is not published, and prospective customers need to ask Advarra for details.
Plans and prices
From Advarra OnCore's own pricing page, checked 4 Oct 2026.
| Plan | Price | What it gives you |
|---|---|---|
| OnCore CTMS | — | Additional modules, such as biospecimen management, are licensed separately · Annual subscription; fee depends on licensed modules and protocol volume. |
The facts
Each one read from Advarra OnCore's own pages, with the date it was checked.
What it does
- Analytics
- OnCore Analytics provides visualizations and insights related to accrual, study activation, staff effort, and other clinical trial operations.checked 4 Oct 2026
- Cancer center reporting
- Advarra describes support for NCI reporting, internal auditing, data safety oversight, automated data table reporting, and PRMC workflows.checked 4 Oct 2026
- EMR integrations
- OnCore connects with Epic and Cerner and supports exchange of subject, protocol, demographic, and billing data with EMR systems.checked 4 Oct 2026
- Hosting and support
- Advarra describes its cloud platform as SaaS hosted on AWS, with cloud technology experts providing system management and support.checked 4 Oct 2026
- Intended users
- Advarra says OnCore typically serves academic medical centers, cancer centers, and some health systems conducting 50 to 500+ active trials.checked 4 Oct 2026
- Other integrations
- Listed integrations include eIRB through the OnCore API, EMR billing grids and demographics, general ledger, OnCore Analytics, and Advarra Payments.checked 4 Oct 2026
- Pricing detail
- The annual subscription covers license, maintenance, support, and upgrades; Advarra directs prospective customers to sales for pricing.checked 4 Oct 2026
- Purpose
- OnCore is a clinical trial management system for managing clinical research operations across a trial’s lifecycle.checked 4 Oct 2026
- Research and finance workflows
- The system supports clinical research management, protocol and participant workflows, budgeting, invoicing, receivables, and billing compliance.checked 4 Oct 2026
- Security and compliance
- Advarra Cloud is described as meeting SOC 2, HIPAA, 21 CFR Part 11, and NIST 800-53 standards.checked 4 Oct 2026
- Specialized modules
- Additional capabilities include biospecimen management, protocol review management, registry management, and Advarra EDC technology for investigator-initiated trials.checked 4 Oct 2026
The company
- Company history
- Advarra says it took its current shape in 2017 when Schulman IRB and Chesapeake IRB came together to form the company.checked 4 Oct 2026
- Headquarters
- Columbia, Maryland, United Stateschecked 28 Sep 2026
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